ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

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C-type lectin domain family 2 member I

Intermolecular
Cysteine 92 and cysteine 92
Intramolecular
Cysteine 92 and cysteine 103
A redox-regulated disulphide may form between two units of C-type lectin domain family 2 member I at cysteines 92 and 92. However, the redox score of this cysteine pair is lower than any known redox-active intermolecular disulphide. ?

Details

Redox score ?
48
PDB code
3rs1
Structure name
mouse c-type lectin-related protein clrg
Structure deposition date
2011-05-02
Thiol separation (Å)
9
Half-sphere exposure sum ?
65
Minimum pKa ?
nan
% buried
nan
Peptide A name
C-type lectin domain family 2 member I
Peptide B name
C-type lectin domain family 2 member I
Peptide A accession
Q9WVF9
Peptide B accession
Q9WVF9
Peptide A residue number
92
Peptide B residue number
92

Ligandability

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

A redox-regulated disulphide may form within C-type lectin domain family 2 member I between cysteines 92 and 103.

Details

Redox score ?
82
PDB code
3rs1
Structure name
mouse c-type lectin-related protein clrg
Structure deposition date
2011-05-02
Thiol separation (Å)
2
Half-sphere exposure sum ?
75
Minimum pKa ?
nan
% buried
nan
Peptide accession
Q9WVF9
Residue number A
92
Residue number B
103
Peptide name
C-type lectin domain family 2 member I

Ligandability

Cysteine 92 of C-type lectin domain family 2 member I

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 103 of C-type lectin domain family 2 member I

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

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